TimeXNet Web - Identify active gene networks and pathways using time-course biological data

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KEGG Pathway Enrichment

Job Name:

LPS Response in Mouse TRIF KO BMDCs

Current Gene List:

Input Gene List

Background List:

Submitted Network

125 chart records

Note: Only the top 1000 records are shown here

Category	Term	Count	%	P-value	Benjamini
KEGG_PATHWAY	mmu04668:TNF signaling pathway	56	6.1	1.3e-23	3.3e-21
KEGG_PATHWAY	mmu05161:Hepatitis B	62	6.7	1.3e-23	1.7e-21
KEGG_PATHWAY	mmu04620:Toll-like receptor signaling pathway	51	5.5	2.6e-22	2.2e-20
KEGG_PATHWAY	mmu05142:Chagas disease (American trypanosomiasis)	53	5.8	1.0e-21	6.5e-20
KEGG_PATHWAY	mmu04722:Neurotrophin signaling pathway	56	6.1	1.4e-21	7.1e-20
KEGG_PATHWAY	mmu05133:Pertussis	42	4.6	2.3e-21	9.8e-20
KEGG_PATHWAY	mmu05169:Epstein-Barr virus infection	71	7.7	5.2e-21	1.9e-19
KEGG_PATHWAY	mmu05145:Toxoplasmosis	49	5.3	5.8e-19	1.8e-17
KEGG_PATHWAY	mmu04010:MAPK signaling pathway	80	8.7	6.9e-19	2.0e-17
KEGG_PATHWAY	mmu04064:NF-kappa B signaling pathway	45	4.9	8.7e-19	2.2e-17
KEGG_PATHWAY	mmu05200:Pathways in cancer	107	11.6	3.3e-18	7.7e-17
KEGG_PATHWAY	mmu05164:Influenza A	58	6.3	3.0e-17	6.5e-16
KEGG_PATHWAY	mmu04621:NOD-like receptor signaling pathway	33	3.6	3.6e-17	7.0e-16
KEGG_PATHWAY	mmu05205:Proteoglycans in cancer	70	7.6	1.3e-16	2.0e-15
KEGG_PATHWAY	mmu05140:Leishmaniasis	32	3.5	4.5e-16	7.5e-15
KEGG_PATHWAY	mmu05152:Tuberculosis	59	6.4	7.2e-16	1.2e-14
KEGG_PATHWAY	mmu04380:Osteoclast differentiation	47	5.1	6.7e-15	1.0e-13
KEGG_PATHWAY	mmu04662:B cell receptor signaling pathway	35	3.8	7.0e-15	9.9e-14
KEGG_PATHWAY	mmu04915:Estrogen signaling pathway	41	4.5	9.1e-14	1.2e-12
KEGG_PATHWAY	mmu05168:Herpes simplex infection	53	5.8	9.8e-14	1.3e-12
KEGG_PATHWAY	mmu05215:Prostate cancer	38	4.1	1.1e-13	1.3e-12
KEGG_PATHWAY	mmu04062:Chemokine signaling pathway	59	6.4	1.3e-13	1.5e-12
KEGG_PATHWAY	mmu04660:T cell receptor signaling pathway	43	4.7	3.6e-13	4.0e-12
KEGG_PATHWAY	mmu04068:FoxO signaling pathway	49	5.3	8.7e-13	9.3e-12
KEGG_PATHWAY	mmu05203:Viral carcinogenesis	59	6.4	1.2e-12	1.2e-11
KEGG_PATHWAY	mmu05160:Hepatitis C	47	5.1	1.2e-12	1.2e-11
KEGG_PATHWAY	mmu05220:Chronic myeloid leukemia	34	3.7	1.3e-12	1.2e-11
KEGG_PATHWAY	mmu05212:Pancreatic cancer	32	3.5	1.8e-12	1.6e-11
KEGG_PATHWAY	mmu05210:Colorectal cancer	31	3.4	3.8e-12	3.4e-11
KEGG_PATHWAY	mmu05206:MicroRNAs in cancer	47	5.1	5.5e-12	4.6e-11
KEGG_PATHWAY	mmu05162:Measles	46	5.0	1.1e-11	9.3e-11
KEGG_PATHWAY	mmu04917:Prolactin signaling pathway	33	3.6	1.4e-11	1.1e-10
KEGG_PATHWAY	mmu05166:HTLV-I infection	69	7.5	1.6e-11	1.2e-10
KEGG_PATHWAY	mmu04912:GnRH signaling pathway	34	3.7	3.1e-11	2.3e-10
KEGG_PATHWAY	mmu04012:ErbB signaling pathway	36	3.9	4.4e-11	3.2e-10
KEGG_PATHWAY	mmu05132:Salmonella infection	33	3.6	1.7e-10	1.2e-9
KEGG_PATHWAY	mmu04664:Fc epsilon RI signaling pathway	30	3.3	2.4e-10	1.6e-9
KEGG_PATHWAY	mmu04910:Insulin signaling pathway	45	4.9	2.5e-10	1.7e-9
KEGG_PATHWAY	mmu04210:Apoptosis	29	3.1	3.0e-10	2.0e-9
KEGG_PATHWAY	mmu05134:Legionellosis	26	2.8	5.6e-10	3.6e-9
KEGG_PATHWAY	mmu05221:Acute myeloid leukemia	25	2.7	1.2e-9	7.4e-9
KEGG_PATHWAY	mmu04071:Sphingolipid signaling pathway	38	4.1	1.2e-9	7.4e-9
KEGG_PATHWAY	mmu04622:RIG-I-like receptor signaling pathway	27	2.9	6.1e-9	3.6e-8
KEGG_PATHWAY	mmu04630:Jak-STAT signaling pathway	41	4.5	2.3e-8	1.3e-7
KEGG_PATHWAY	mmu04650:Natural killer cell mediated cytotoxicity	33	3.6	4.2e-8	2.4e-7
KEGG_PATHWAY	mmu04510:Focal adhesion	51	5.5	4.2e-8	2.3e-7
KEGG_PATHWAY	mmu04370:VEGF signaling pathway	25	2.7	6.8e-8	3.7e-7
KEGG_PATHWAY	mmu04015:Rap1 signaling pathway	52	5.6	8.4e-8	4.5e-7
KEGG_PATHWAY	mmu05223:Non-small cell lung cancer	24	2.6	9.2e-8	4.8e-7
KEGG_PATHWAY	mmu04611:Platelet activation	37	4.0	1.1e-7	5.4e-7
KEGG_PATHWAY	mmu05213:Endometrial cancer	22	2.4	1.6e-7	8.2e-7
KEGG_PATHWAY	mmu05202:Transcriptional misregulation in cancer	38	4.1	2.8e-7	1.4e-6
KEGG_PATHWAY	mmu05211:Renal cell carcinoma	24	2.6	3.3e-7	1.6e-6
KEGG_PATHWAY	mmu05222:Small cell lung cancer	29	3.1	3.5e-7	1.7e-6
KEGG_PATHWAY	mmu04060:Cytokine-cytokine receptor interaction	54	5.9	4.2e-7	1.9e-6
KEGG_PATHWAY	mmu05219:Bladder cancer	18	2.0	7.4e-7	3.4e-6
KEGG_PATHWAY	mmu05144:Malaria	18	2.0	7.4e-7	3.4e-6
KEGG_PATHWAY	mmu04920:Adipocytokine signaling pathway	26	2.8	7.5e-7	3.3e-6
KEGG_PATHWAY	mmu04151:PI3K-Akt signaling pathway	70	7.6	1.3e-6	5.7e-6
KEGG_PATHWAY	mmu04914:Progesterone-mediated oocyte maturation	28	3.0	1.8e-6	7.8e-6
KEGG_PATHWAY	mmu04141:Protein processing in endoplasmic reticulum	42	4.6	2.3e-6	9.9e-6
KEGG_PATHWAY	mmu04932:Non-alcoholic fatty liver disease (NAFLD)	39	4.2	2.5e-6	1.1e-5
KEGG_PATHWAY	mmu05146:Amoebiasis	30	3.3	2.6e-6	1.1e-5
KEGG_PATHWAY	mmu05321:Inflammatory bowel disease (IBD)	20	2.2	2.8e-6	1.1e-5
KEGG_PATHWAY	mmu04931:Insulin resistance	31	3.4	4.0e-6	1.6e-5
KEGG_PATHWAY	mmu05020:Prion diseases	15	1.6	4.2e-6	1.6e-5
KEGG_PATHWAY	mmu04022:cGMP-PKG signaling pathway	39	4.2	4.7e-6	1.8e-5
KEGG_PATHWAY	mmu04066:HIF-1 signaling pathway	30	3.3	5.8e-6	2.2e-5
KEGG_PATHWAY	mmu04024:cAMP signaling pathway	44	4.8	6.3e-6	2.4e-5
KEGG_PATHWAY	mmu05214:Glioma	22	2.4	8.9e-6	3.3e-5
KEGG_PATHWAY	mmu05143:African trypanosomiasis	14	1.5	8.9e-6	3.2e-5
KEGG_PATHWAY	mmu04550:Signaling pathways regulating pluripotency of stem cells	36	3.9	1.2e-5	4.2e-5
KEGG_PATHWAY	mmu04923:Regulation of lipolysis in adipocytes	20	2.2	1.3e-5	4.6e-5
KEGG_PATHWAY	mmu04014:Ras signaling pathway	48	5.2	1.9e-5	6.7e-5
KEGG_PATHWAY	mmu04921:Oxytocin signaling pathway	37	4.0	2.2e-5	7.5e-5
KEGG_PATHWAY	mmu04320:Dorso-ventral axis formation	12	1.3	2.2e-5	7.6e-5
KEGG_PATHWAY	mmu04520:Adherens junction	22	2.4	2.3e-5	7.7e-5
KEGG_PATHWAY	mmu05014:Amyotrophic lateral sclerosis (ALS)	19	2.1	2.6e-5	8.7e-5
KEGG_PATHWAY	mmu05231:Choline metabolism in cancer	26	2.8	3.4e-5	0.00011
KEGG_PATHWAY	mmu04623:Cytosolic DNA-sensing pathway	19	2.1	5.2e-5	0.00017
KEGG_PATHWAY	mmu04750:Inflammatory mediator regulation of TRP channels	27	2.9	0.00014	0.00046
KEGG_PATHWAY	mmu04720:Long-term potentiation	19	2.1	0.00023	0.00071
KEGG_PATHWAY	mmu04350:TGF-beta signaling pathway	24	2.6	0.00023	0.00073
KEGG_PATHWAY	mmu04114:Oocyte meiosis	27	2.9	0.00032	0.00097
KEGG_PATHWAY	mmu04919:Thyroid hormone signaling pathway	27	2.9	0.00038	0.0012
KEGG_PATHWAY	mmu04930:Type II diabetes mellitus	16	1.7	0.00041	0.0012
KEGG_PATHWAY	mmu05216:Thyroid cancer	11	1.2	0.00041	0.0012
KEGG_PATHWAY	mmu04270:Vascular smooth muscle contraction	26	2.8	0.00046	0.0013
KEGG_PATHWAY	mmu04730:Long-term depression	17	1.8	0.00049	0.0014
KEGG_PATHWAY	mmu04110:Cell cycle	30	3.3	0.00073	0.0021
KEGG_PATHWAY	mmu05230:Central carbon metabolism in cancer	18	2.0	0.00091	0.0026
KEGG_PATHWAY	mmu04540:Gap junction	21	2.3	0.0011	0.003
KEGG_PATHWAY	mmu04144:Endocytosis	45	4.9	0.002	0.0055
KEGG_PATHWAY	mmu04670:Leukocyte transendothelial migration	27	2.9	0.0023	0.0064
KEGG_PATHWAY	mmu04810:Regulation of actin cytoskeleton	40	4.3	0.0026	0.0069
KEGG_PATHWAY	mmu04115:p53 signaling pathway	17	1.8	0.0026	0.007
KEGG_PATHWAY	mmu04666:Fc gamma R-mediated phagocytosis	21	2.3	0.0027	0.0073
KEGG_PATHWAY	mmu05218:Melanoma	18	2.0	0.004	0.01
KEGG_PATHWAY	mmu05323:Rheumatoid arthritis	17	1.8	0.0047	0.012
KEGG_PATHWAY	mmu04728:Dopaminergic synapse	26	2.8	0.0092	0.024
KEGG_PATHWAY	mmu05100:Bacterial invasion of epithelial cells	19	2.1	0.01	0.026
KEGG_PATHWAY	mmu04640:Hematopoietic cell lineage	18	2.0	0.011	0.027
KEGG_PATHWAY	mmu04261:Adrenergic signaling in cardiomyocytes	28	3.0	0.011	0.028
KEGG_PATHWAY	mmu05416:Viral myocarditis	13	1.4	0.012	0.029
KEGG_PATHWAY	mmu04360:Axon guidance	25	2.7	0.012	0.03
KEGG_PATHWAY	mmu04725:Cholinergic synapse	22	2.4	0.013	0.032
KEGG_PATHWAY	mmu04970:Salivary secretion	14	1.5	0.017	0.04
KEGG_PATHWAY	mmu04916:Melanogenesis	20	2.2	0.028	0.065
KEGG_PATHWAY	mmu04612:Antigen processing and presentation	12	1.3	0.029	0.068
KEGG_PATHWAY	mmu04925:Aldosterone synthesis and secretion	15	1.6	0.03	0.069
KEGG_PATHWAY	mmu04713:Circadian entrainment	18	2.0	0.032	0.073
KEGG_PATHWAY	mmu04310:Wnt signaling pathway	25	2.7	0.035	0.079
KEGG_PATHWAY	mmu05340:Primary immunodeficiency	10	1.1	0.037	0.082
KEGG_PATHWAY	mmu05034:Alcoholism	24	2.6	0.038	0.084
KEGG_PATHWAY	mmu04960:Aldosterone-regulated sodium reabsorption	10	1.1	0.044	0.096
KEGG_PATHWAY	mmu04918:Thyroid hormone synthesis	13	1.4	0.044	0.096
KEGG_PATHWAY	mmu05330:Allograft rejection	8	0.9	0.045	0.096
KEGG_PATHWAY	mmu04940:Type I diabetes mellitus	9	1.0	0.045	0.095
KEGG_PATHWAY	mmu04924:Renin secretion	12	1.3	0.047	0.099
KEGG_PATHWAY	mmu05332:Graft-versus-host disease	7	0.8	0.054	0.11
KEGG_PATHWAY	mmu04120:Ubiquitin mediated proteolysis	23	2.5	0.064	0.13
KEGG_PATHWAY	mmu00220:Arginine biosynthesis	6	0.7	0.083	0.17
KEGG_PATHWAY	mmu05031:Amphetamine addiction	12	1.3	0.09	0.18
KEGG_PATHWAY	mmu04971:Gastric acid secretion	13	1.4	0.093	0.18
KEGG_PATHWAY	mmu04710:Circadian rhythm	8	0.9	0.093	0.18